HTTP Error 500.19 - Internal Server Error The requested page cannot be accessed because the related

HTTP Error 500.19 - Internal Server Error The requested page cannot be accessed because the related configuration data for the page is invalid

Module IIS WebCoreNotificationUnknownHandlerNot yet determined
ErrorCode0x80070005ConfigErrorCannot read configuration file due to insufficient permissions
ConfigFile \?C:UsersYassoDocumentsVisual Studio2008WebSitesWebSite5web.config
SOLUTION :
Right click on folder you need to give security permission to. 
This is the root folder where you application is published and is the same folder 
as your IIS website physical path. Choose properties from the context menu 
and click on the Security tab. Edit users, and then Add a user. 
Click the Locations button and choose the top icon (looks like My Computer). 
In the text area, enter IIS_IUSRS. Press OKs repeatedly until all context menus are close. 
Restart your web site and navigate to it again.